American journal of ophthalmology · 2005
Visual loss as a first sign of adult-type chronic myeloid leukemia in a child.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Rudolph Günther, Haritoglou Christos, Schmid Irene, Hochhaus Friedericke, Kampik Anselm
Аннотация
PURPOSE: To report the unusual case of retinal leukemic infiltration in a child with adult-type chronic myelocytic leukemia.
DESIGN: Interventional case report.
METHODS: Complete ophthalmologic examination, including visual acuity measurement and funduscopy. The diagnosis was established by blood cell counts and confirmed by a positive Philadelphia-chromosome translocation (t [9,22]). Treatment consisted of hydroxyurea and stem-cell transplantation.
RESULTS: After therapy, complete regression of the retinal lesion was observed with full recovery of visual acuity.
CONCLUSION: This case underlines the importance of interdisciplinary cooperation between ophthalmologists and pediatric oncologists in the diagnosis and treatment of this disease.
DESIGN: Interventional case report.
METHODS: Complete ophthalmologic examination, including visual acuity measurement and funduscopy. The diagnosis was established by blood cell counts and confirmed by a positive Philadelphia-chromosome translocation (t [9,22]). Treatment consisted of hydroxyurea and stem-cell transplantation.
RESULTS: After therapy, complete regression of the retinal lesion was observed with full recovery of visual acuity.
CONCLUSION: This case underlines the importance of interdisciplinary cooperation between ophthalmologists and pediatric oncologists in the diagnosis and treatment of this disease.