Future microbiology · 2022
Multilocus sequence typing of Treponema pallidum pallidum in children with acquired syphilis by nonsexual contact.
СтатьяНазвание и аннотация: Перевод в очереди
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Garcia Luciana N, Morando Nicolás, Otero Adrián V, Moroni Samanta, Moscatelli Guillermo F, Gonzalez Nicolás, D Slojan Alejandra, Lascano Fernanda, Ballering Griselda, Pando Maria A, Altcheh Jaime M
Аннотация
Background: There are scarce data of Treponema pallidum subsp. pallidum (TPA) characterization in children with syphilis. Nonsexually acquired transmission (NSAT) of TPA is possible in infants through close contact. Methods: A descriptive study in five families with NSAT of syphilis was conducted. Polymerase chain reaction detection of TPA in pediatric index cases (n = 6) and their relatives (n = 44) were conducted followed by multilocus sequence typing (MLST). Results: TPA was detected in swab samples in 16 cases and 12 were characterized by MLST. Nichols lineage was identified in two of five families and SS14-lineage in three of five. In four families, MLST profiles linked index cases to relatives. Conclusion: This is the first report of TPA characterization in children infected by NSAT.