Journal of clinical periodontology · 2012
Clinical utility of a novel colorimetric chair side test for oral malodour.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Dadamio Jesica, Van Tornout Marie, Vancauwenberghe Frederique, Federico Rodolfo, Dekeyser Christel, Quirynen Marc
Аннотация
AIM: The aim of this study was to evaluate the utility of a simple colorimetric chair side test detecting amines in saliva as an adjunct test in the oral malodour diagnosis.
MATERIAL AND METHODS: Non-stimulated saliva samples were collected from 100 volunteers with different degrees of oral malodour. The amount of amines detected by the test was estimated clinically (colorimetric test), confirmed semi quantitatively in the laboratory (standard addition method) and consequently compared with (i) the organoleptic score (OLS); (ii) the volatile sulphur compounds (VSCs) levels (OralChroma(™)) and (iii) the amount of amines detected by means of gas chromatography - mass spectroscopy.
RESULTS: The chair side test correlated well (Spearman correlation coefficient: 0.46-0.77), with the OLS, the level of VSCs, and the amines determined by using gas chromatography - mass spectroscopy. The results of the new test for patients with and without oral malodour were significantly different (Mann-Whitney U-test, p < 0.0001). The sensitivity, specificity, and positive and negative predictive value of this chair side test were similar to those of the VSCs evaluations.
CONCLUSIONS: These results support the "fit for purpose" of the new chair side test as adjunctive diagnostic tool for oral malodour.
MATERIAL AND METHODS: Non-stimulated saliva samples were collected from 100 volunteers with different degrees of oral malodour. The amount of amines detected by the test was estimated clinically (colorimetric test), confirmed semi quantitatively in the laboratory (standard addition method) and consequently compared with (i) the organoleptic score (OLS); (ii) the volatile sulphur compounds (VSCs) levels (OralChroma(™)) and (iii) the amount of amines detected by means of gas chromatography - mass spectroscopy.
RESULTS: The chair side test correlated well (Spearman correlation coefficient: 0.46-0.77), with the OLS, the level of VSCs, and the amines determined by using gas chromatography - mass spectroscopy. The results of the new test for patients with and without oral malodour were significantly different (Mann-Whitney U-test, p < 0.0001). The sensitivity, specificity, and positive and negative predictive value of this chair side test were similar to those of the VSCs evaluations.
CONCLUSIONS: These results support the "fit for purpose" of the new chair side test as adjunctive diagnostic tool for oral malodour.
Предметные рубрики MeSH
AdolescentAdultAgedAminesColorimetryDental PlaqueDisulfidesFemaleGas Chromatography-Mass SpectrometryGingivitisHalitosisHemiterpenesHumansHydrogen SulfideMaleMiddle AgedOral Hygiene IndexPentanoic AcidsPeriodontal PocketPoint-of-Care SystemsPutrescineSalivaSensitivity and SpecificitySkatoleSulfhydryl CompoundsSulfidesSulfur CompoundsTongueVolatile Organic CompoundsYoung Adult