[Congenital glaucoma in Hurler's syndrome and in Lowe's syndrome. Clinical and electron microscopy findings].

2 cases of congenital glaucoma combined with a general metabolic disease are described. 1 patient displayed the symptoms of a mucopolysaccharidosis (Hurler's syndrome), the other patient showed the characteristics of Lowe's oculo-cerebrorenal syndrome. In both patients a surgical trabeculectomy was performed. The excised tissues were analysed by electron microscopy. Distinct vacuolar or fibrillar deposits were observed in both cases in the trabecular region and in Schlemm's canal. Possibly, these alterations could have contributed to the raised intraocular pressure in both patients.