The Medical journal of Australia · 1993
Hypothermia, hyperhidrosis, myokymia and increased urinary excretion of catecholamines associated with a thymoma.
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Ho W K, Wilson J D
Аннотация
OBJECTIVE: To report a rare syndrome associated with a thymoma and its first successful treatment with gammaglobulin.
CLINICAL FEATURES: A 49-year-old white male presented with marked hypothermia, hyperhidrosis, myokymia and increased urinary excretion of catecholamines four weeks after complete excision of a malignant thymoma. He became increasingly drowsy, obtunded and required ventilatory support.
INTERVENTION AND OUTCOME: A catecholamine secreting tumour was excluded and he was treated with intravenous gammaglobulin for five days, with dramatic improvement in his condition. Six months later he remains in remission.
CONCLUSION: The response to treatment in this patient suggests an immunological pathogenesis for this rare group of symptoms associated with a thymoma.
CLINICAL FEATURES: A 49-year-old white male presented with marked hypothermia, hyperhidrosis, myokymia and increased urinary excretion of catecholamines four weeks after complete excision of a malignant thymoma. He became increasingly drowsy, obtunded and required ventilatory support.
INTERVENTION AND OUTCOME: A catecholamine secreting tumour was excluded and he was treated with intravenous gammaglobulin for five days, with dramatic improvement in his condition. Six months later he remains in remission.
CONCLUSION: The response to treatment in this patient suggests an immunological pathogenesis for this rare group of symptoms associated with a thymoma.