Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia.
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Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Faughnan Marie E, Mager Johannes J, Hetts Steven W, Palda Valerie A, Lang-Robertson Kelly, Buscarini Elisabetta, Deslandres Erik, Kasthuri Raj S, Lausman Andrea, Poetker David, Ratjen Felix, Chesnutt Mark S, Clancy Marianne, Whitehead Kevin J, Al-Samkari Hanny, Chakinala Murali, Conrad Miles, Cortes Daniel, Crocione Claudia, Darling Jama, de Gussem Els, Derksen Carol, Dupuis-Girod Sophie, Foy Patrick, Geisthoff Urban, Gossage James R, Hammill Adrienne, Heimdal Ketil, Henderson Katharine, Iyer Vivek N, Kjeldsen Anette D, Komiyama Masaki, Korenblatt Kevin, McDonald Jamie, McMahon Jack, McWilliams Justin, Meek Mary E, Mei-Zahav Meir, Olitsky Scott, Palmer Sara, Pantalone Rose, Piccirillo Jay F, Plahn Beth, Porteous Mary E M, Post Marco C, Radovanovic Ivan, Rochon Paul J, Rodriguez-Lopez Josanna, Sabba Carlo, Serra Marcelo, Shovlin Claire, Sprecher Dennis, White Andrew J, Winship Ingrid, Zarrabeitia Roberto
Аннотация
METHODS: The guidelines were developed using the AGREE II (Appraisal of Guidelines for Research and Evaluation II) framework and GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology. The guidelines expert panel included expert physicians (clinical and genetic) in HHT from 15 countries, guidelines methodologists, health care workers, health care administrators, patient advocacy representatives, and persons with HHT. During the preconference process, the expert panel generated clinically relevant questions in 6 priority topic areas. A systematic literature search was done in June 2019, and articles meeting a priori criteria were included to generate evidence tables, which were used as the basis for recommendation development. The expert panel subsequently convened during a guidelines conference to conduct a structured consensus process, during which recommendations reaching at least 80% consensus were discussed and approved.
RECOMMENDATIONS: The expert panel generated and approved 6 new recommendations for each of the following 6 priority topic areas: epistaxis, gastrointestinal bleeding, anemia and iron deficiency, liver VMs, pediatric care, and pregnancy and delivery (36 total). The recommendations highlight new evidence in existing topics from the first International HHT Guidelines and provide guidance in 3 new areas: anemia, pediatrics, and pregnancy and delivery. These recommendations should facilitate implementation of key components of HHT care into clinical practice.