[Study on anti-HPV activity of Asarum heterotropoides].

OBJECTIVE

To screen anti-HPV effective fraction from Asarum heterotropoides.

METHODS

Asarum heterotropoides was extracted with systematic solvents (petroleum benzine, ether, ethyl acetate, n-butanol, ethanol and distilled water) accordingly. The Polymerase Chain Reaction (FQ-PCR) was applied in the vitro pharmacodynamics for the extracts from Asarum heterotropoides. The amplification of HPV-DNA in the lesions of the isolated Condyloma acuminatum.

RESULTS

After the water extracts of Asarum heterotropoides was used for HPV-DNA, the PCR amplification showed negative, with the minimum effective concentration 0.4 g/ml. But the other solvents extracts from Asarum heterotropoides appeared positive.

CONCLUSION

The water extracts from Asarum heterotropoides are effective on anti-Human papillomavirus.