European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2025
Life is an ongoing existential battle - experiences from adult survivors after allogeneic hematopoietic stem cell transplantation during childhood acute lymphoblastic leukemia.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Olsson Maria, Aili Katarina, Jarfelt Marianne, Nygren Jens M, Arvidsson Susann
Аннотация
PURPOSE: The present study aimed to provide insight into how adult survivors describe their experiences concerning health, lifestyle, and quality of life, considering the long-term impact of treatment for acute lymphoblastic leukemia (ALL) and allogeneic HSCT (a-HSCT) during their childhood. The research question focused on understanding the long-term effects of these treatments on survivors' lives.
METHODS: A descriptive and qualitative design was employed. Participants included eighteen individuals who had undergone a-HSCT for childhood ALL and were part of a national cohort diagnosed between 1985 and 2007. Data were collected through semi-structured telephone interviews, with questions assessing current health, quality of life, and the impact of childhood cancer experiences on their lifestyle. Interviews were transcribed verbatim and analyzed using an inductive approach and thematic analysis to identify key themes.
RESULTS: The analysis revealed two overarching themes: "Challenges and adaptation in long-term survivorship" and "Uncertainty and doubts surrounding parenthood," with five subthemes. Participants described ongoing existential struggles, both internal (maintaining health despite complications) and external (social participation difficulties). They also faced emotional distress related to infertility and doubts about their suitability as parents.
CONCLUSIONS: The study highlights the profound personal challenges faced by childhood ALL survivors treated with a-HSCT. These include managing long-term health complications and existential issues. Support for these individuals should be personalized, addressing medical, emotional, and existential needs to enhance their quality of life. Healthcare professionals at long-term follow-up clinics must address not only the medical but also the emotional and existential challenges faced by adult survivors of childhood cancer to improve their overall quality of life.
METHODS: A descriptive and qualitative design was employed. Participants included eighteen individuals who had undergone a-HSCT for childhood ALL and were part of a national cohort diagnosed between 1985 and 2007. Data were collected through semi-structured telephone interviews, with questions assessing current health, quality of life, and the impact of childhood cancer experiences on their lifestyle. Interviews were transcribed verbatim and analyzed using an inductive approach and thematic analysis to identify key themes.
RESULTS: The analysis revealed two overarching themes: "Challenges and adaptation in long-term survivorship" and "Uncertainty and doubts surrounding parenthood," with five subthemes. Participants described ongoing existential struggles, both internal (maintaining health despite complications) and external (social participation difficulties). They also faced emotional distress related to infertility and doubts about their suitability as parents.
CONCLUSIONS: The study highlights the profound personal challenges faced by childhood ALL survivors treated with a-HSCT. These include managing long-term health complications and existential issues. Support for these individuals should be personalized, addressing medical, emotional, and existential needs to enhance their quality of life. Healthcare professionals at long-term follow-up clinics must address not only the medical but also the emotional and existential challenges faced by adult survivors of childhood cancer to improve their overall quality of life.