Zhonghua fu chan ke za zhi · 1999
[Effects of human papillomavirus infection on pregnant women and chorionic trophoblasts].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Chen X, Zhao C, Zhang Y
Аннотация
OBJECTIVE: To evaluate the effects of human papilloma virus (HPV) infection on pregnant women and chorionic trophoblasts.
METHODS: The morphological characters were observed from 62 pregnant women with codyloma acuminatum during the first and second trimester. In situ hybridization (ISH) was performed to detect HPV 6/11 in chorionic villi of all these cases. In 10 cases, ISH was also performed in condyloma acuminatum of vulva, vaginal and cervix. In 10 cases HPV 6/11 was detected by polymerase chain reaction (PCR) in chorionic villi as well.
RESULTS: The lesions condyloma acuminatum developed rapidly during pregnancy. Multiple lesions were found usually, and the gross appearances and histological features were more typical. Using ISH and PCR to detect HPV 6/11-DNA in chorionic villi all showed negative. 8 of 10 cases were positive in condyloma acuminatum sites by ISH.
CONCLUSIONS: HPV infection does not make vertical transmission during first and second trimester. It does not increase the potential risk for the fetus.
METHODS: The morphological characters were observed from 62 pregnant women with codyloma acuminatum during the first and second trimester. In situ hybridization (ISH) was performed to detect HPV 6/11 in chorionic villi of all these cases. In 10 cases, ISH was also performed in condyloma acuminatum of vulva, vaginal and cervix. In 10 cases HPV 6/11 was detected by polymerase chain reaction (PCR) in chorionic villi as well.
RESULTS: The lesions condyloma acuminatum developed rapidly during pregnancy. Multiple lesions were found usually, and the gross appearances and histological features were more typical. Using ISH and PCR to detect HPV 6/11-DNA in chorionic villi all showed negative. 8 of 10 cases were positive in condyloma acuminatum sites by ISH.
CONCLUSIONS: HPV infection does not make vertical transmission during first and second trimester. It does not increase the potential risk for the fetus.