Flat wart of the urethra caused by human papillomavirus type 16.

A rare case of urethral flat wart caused by human papillomavirus (HPV) type 16 was reported. A 34-year-old male consulted our department with a complaint of urethral bleeding. A pair of symmetrical white flat warts combined with ulcer at the urethral meatus were found. Microscopic examination of the specimen demonstrated koilocytosis of the epithelium. In immunohistochemical study it was positive for HPV and HPV type 16 was detected by polymerase chain reaction.