Jornal de pediatria · 2010
Open challenge for the diagnosis of cow's milk protein allergy.
Оценочное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Correa Fernanda Ferreira, Vieira Mário César, Yamamoto Danielle Reis, Speridião Patrícia da Graça Leite, de Morais Mauro Batista
Аннотация
OBJECTIVE: To report the results of open challenge tests performed in children fed with cow's milk-free diet.
DESCRIPTION: Cross-sectional study evaluating cow's milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred. One hundred and twenty-one patients were included, with ages between 4 and 95 months. Cow's milk open challenge tests were positive in 28 patients (23.1%). A clinical manifestation of cow's milk allergy different from the one presented at diagnosis occurred in 12 (24.9%) patients with positive challenge. Positive challenge was more frequent (p = 0.042) in patients fed with extensively hydrolyzed formulae or amino acid-based formulae (30.3%) when compared to those fed with other exclusion diets (14.5%).
CONCLUSION: Open challenge allowed the interruption of exclusion diet in a significant proportion of the patients.
DESCRIPTION: Cross-sectional study evaluating cow's milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred. One hundred and twenty-one patients were included, with ages between 4 and 95 months. Cow's milk open challenge tests were positive in 28 patients (23.1%). A clinical manifestation of cow's milk allergy different from the one presented at diagnosis occurred in 12 (24.9%) patients with positive challenge. Positive challenge was more frequent (p = 0.042) in patients fed with extensively hydrolyzed formulae or amino acid-based formulae (30.3%) when compared to those fed with other exclusion diets (14.5%).
CONCLUSION: Open challenge allowed the interruption of exclusion diet in a significant proportion of the patients.