Multisystem inflammatory syndrome in children treated at a hospital in Yucatan.

BACKGROUND

Multisystem inflammatory syndrome in children (MIS-C) has not been described in southeastern Mexico.

OBJECTIVE

To report the clinical and epidemiological aspects of MIS-C in a private hospital in Mérida, Yucatán.

MATERIAL AND

METHODS

Retrospective, descriptive, consecutive case series study in children under 18 years of age, treated from January 2021 to March 2024. Patients diagnosed with MIS-C were selected. Patients underwent PCR testing, serological testing, or had known exposure to a family member with COVID-19. Descriptive statistics were analyzed with the X2 test.

RESULTS

Seventy patients were included: 59 (84%) were hospitalized and 11 (16%) were followed up in the outpatient clinic, all with a diagnosis of MIS-C, median age 48 months (4-192), 44 (74.58%) were < 5 years old (p < 0.001) and predominance of males with 36 (61%). Of the hospitalized cases, 40 (67.79%) had the MIS-C phenotype and 19 (32.2%) had Kawasaki disease and MIS-C. MIS-C predominated in those aged ≤ 60 months. Gastrointestinal symptoms predominated in 68.5% of cases, and cardiovascular symptoms in 68.5%. There were 6 cases with coronary aneurysms (8.5%).

CONCLUSIONS

Cases were most frequent in those aged < 5 years, with gastrointestinal and cardiovascular symptoms predominating. The presence of coronary aneurysms was low.