Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology · 2008
The efficacy of preemptive ketamine and ropivacaine in pediatric patients: a placebo controlled, double-blind.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Köknel Talu Gül, Ozyalçin N Süleyman, Balsak Rukiye, Karadeniz Meltem
Аннотация
OBJECTIVE: We have evaluated and compared the preemptive efficacy of intravenous ketamine with placebo and caudal ropivacaine in pediatric patients going under elective hernia repair.
METHODS: 60 ASAI-II pediatric patients ages between 1-12. The patients were divided into 3 groups randomly. Group K patients had 0.5mg/kg ketamine by intravenous route before induction,Group R patients had 0.7 mg/kg 0.2% ropivacaine caudally and 2ml normal saline intravenously,Group RK patients had 0.7 mg/kg 0.2% ropivacaine caudally and 0.5mg/kg ketamine by intravenous routeAll patients had standard anesthesia technique. Heart rate (HR), pulse oximetry, and systolic and diastolic blood pressure (BP), and BIS (bispectral index) were obtained during anesthesia, In addition, end-tidal carbon dioxide concentration was monitored. The efficacy of postoperative analgesia was documented by objective pain scale (OPS). Analgesic requirements during and after the surgery documented
RESULTS: While there was no significant differences in fentanyl consumption between the groups GR and GRK, fentanyl consumption was found to be significantly higher in group K during anesthesia.When compared with GR and GRK, GK had significantly higher OPS values. During postoperative period Group K patients demanded for additional analgesics in significantly shorter time than group R and Group K patients. GK patients had consumed significantly higher amounts of acetaminophen after surgery
CONCLUSION: Caudal application of ropivacaine in appropriate doses provides satisfactory peroperative and postoperative analgesia with no side effects in pediatric patient group going under elective hernia repair where as ketamine with the applied doses has no preemptive effect.
METHODS: 60 ASAI-II pediatric patients ages between 1-12. The patients were divided into 3 groups randomly. Group K patients had 0.5mg/kg ketamine by intravenous route before induction,Group R patients had 0.7 mg/kg 0.2% ropivacaine caudally and 2ml normal saline intravenously,Group RK patients had 0.7 mg/kg 0.2% ropivacaine caudally and 0.5mg/kg ketamine by intravenous routeAll patients had standard anesthesia technique. Heart rate (HR), pulse oximetry, and systolic and diastolic blood pressure (BP), and BIS (bispectral index) were obtained during anesthesia, In addition, end-tidal carbon dioxide concentration was monitored. The efficacy of postoperative analgesia was documented by objective pain scale (OPS). Analgesic requirements during and after the surgery documented
RESULTS: While there was no significant differences in fentanyl consumption between the groups GR and GRK, fentanyl consumption was found to be significantly higher in group K during anesthesia.When compared with GR and GRK, GK had significantly higher OPS values. During postoperative period Group K patients demanded for additional analgesics in significantly shorter time than group R and Group K patients. GK patients had consumed significantly higher amounts of acetaminophen after surgery
CONCLUSION: Caudal application of ropivacaine in appropriate doses provides satisfactory peroperative and postoperative analgesia with no side effects in pediatric patient group going under elective hernia repair where as ketamine with the applied doses has no preemptive effect.