Long-term control after stereotactic body radiotherapy for perineal recurrence of prostate cancer after radical prostatectomy and radiotherapy: A case report and review of the literature.

In this article, we report a case of perineal recurrence of prostate cancer occurring 9 years after postoperative radiotherapy following radical prostatectomy for localized prostate cancer. We describe the use of stereotactic body radiotherapy as a potential ablative treatment. Pelvic magnetic resonance imaging identified an 8-mm lesion located below the penile root on the left side, which was distinct from the prostatectomy site. Recurrence was proven by biopsy. Stereotactic body radiotherapy delivered 36Gy in six fractions every other day. The patient showed no recurrence or toxicity by 55 months of follow-up. To the best of our knowledge, this is the first reported case of perineal recurrence successfully treated using stereotactic body radiotherapy.