[Multiple papilloma virus particles in perianal condylomata acuminata of a drug-dependent patient].

A 24-year-old male drug-dependent patient with perianal exophytic condylomata acuminata is reported. An increased production of papillomaviruses could be demonstrated by means of electron microscopy and immunocytochemistry (peroxidase-antiperoxidase technique). This is in contrast to earlier investigations of exophytic condylomata acuminata, which revealed characteristically small amounts of mature papillomavirus particles. The basis for the different form of papillomavirus infection of the anogenital region in this drug-dependent patient is discussed.