American journal of industrial medicine · 2013
Respiratory effects of bioaerosols: exposure-response study among salmon-processing workers.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Shiryaeva Olga, Aasmoe Lisbeth, Straume Bjørn, Olsen Ann-Helen, Øvrum Arild, Kramvik Eva, Larsen Merethe, Renstrøm Anne, Merritt Anne-Sophie, Heldal Kari Kulvik, Bang Berit Elisabeth
Аннотация
OBJECTIVES: The aim of the study was to determine exposure-response relationships in salmon-processing workers.
METHODS: Cross-shift FEV1, acute respiratory symptoms, and exposure to total protein, parvalbumin and endotoxin were main variables measured during one workweek. Exposure-response relationships were analyzed by Generalized Estimation Equations of cross-week data and by multiple regressions of day-to-day data.
RESULTS: Exposure levels were higher in those workers who reported use of water hose. GEE showed negative coefficients for interaction between TP exposure and time (days) on cross-week change of FEV1. Multiple regressions showed significant associations between TP levels and cross-shift change of FEV1 and symptoms (cough, chest tightness) only for Monday shifts.
CONCLUSIONS: A tolerance effect during the course of a workweek is suggested. Use of water hose is a risk process with regard to the liberation of measured components of bioaerosols.
METHODS: Cross-shift FEV1, acute respiratory symptoms, and exposure to total protein, parvalbumin and endotoxin were main variables measured during one workweek. Exposure-response relationships were analyzed by Generalized Estimation Equations of cross-week data and by multiple regressions of day-to-day data.
RESULTS: Exposure levels were higher in those workers who reported use of water hose. GEE showed negative coefficients for interaction between TP exposure and time (days) on cross-week change of FEV1. Multiple regressions showed significant associations between TP levels and cross-shift change of FEV1 and symptoms (cough, chest tightness) only for Monday shifts.
CONCLUSIONS: A tolerance effect during the course of a workweek is suggested. Use of water hose is a risk process with regard to the liberation of measured components of bioaerosols.