Diphtheria, pertussis, and tetanus: an update of evidence-based management of pediatric patients in the emergency department.

Diphtheria, pertussis, and tetanus are potentially deadly illnesses that are largely preventable through vaccination, though they remain in the population. This review discusses the epidemiology, pathophysiology, diagnosis, and current recommended management of these conditions in the emergency department. Disease-specific medications and treatment of secondary complications are reviewed in light of the best current evidence. Issues regarding vaccination and prevention are highlighted.