Boletin medico del Hospital Infantil de Mexico · 1992
[AIDS in children. Experience at the National Institute of Pediatrics].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Desinor-Mompoint O I, González-Saldaña N, Palacios-Saucedo G, Gutiérrez-Ortiz B, de León-Bojorge B, Vázquez-Rivera M
Аннотация
We describe retrospectively the experience with 44 cases of AIDS from January 1987 to October 1991 at the Instituto Nacional de Pediatria, a tertiary care children hospital in Mexico City. All patients with 2 ELISA and a positive Western Blot test were included. Thirty three patients were infected perinatally (75%) and 11 through blood transfusion (25%). Fourty one patients belonged to the P2 classification of the Centers for Disease Control. Chronic diarrhea (77%), lymphadenopathy (75%), hepatomegaly/splenomegaly (70%) and oral candidiasis (61%) were the most common clinical findings. Twenty patients died (45.4%). No statistical relation were found between survival rate and the way of transmission and age at onset. Autopsy was performed in 14 patients and revealed a sharp decrease of lymphoid tissue at all levels with severe thymic atrophy.