The Annals of thoracic surgery · 1999
Intermediate-term results in pediatric aortic valve replacement.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Lupinetti F M, Duncan B W, Scifres A M, Fearneyhough C T, Kilian K, Rosenthal G L, Cecchin F, Jones T K, Herndon S P
Аннотация
BACKGROUND: Aortic valve replacement (AVR) in children is now more commonly performed with human tissue valves.
METHODS: The results of 100 consecutive pediatric AVRs (50 mechanical, 50 human) were reviewed.
RESULTS: There were five perioperative deaths in the mechanical group and one in the human group (p = 0.2). Late complications in the mechanical group included 4 late deaths, 2 cases of endocarditis, 3 thromboembolic complications, and 10 reoperations on the aortic valve. In the human group, there were no late deaths, 2 reoperations for allograft aortic valve deterioration (both in Marfan's patients), and 1 reoperation for allograft pulmonary valve stenosis. Four-year actuarial survival was 83% in the mechanical group and 98% in the human group (p = 0.02). Four-year actuarial survival free of all valve-related complications was 61% in the mechanical group and 88% in the human group (p = 0.008).
CONCLUSIONS: Human valves in children requiring AVR provide superior intermediate-term survival and freedom from valve-related complications compared to mechanical valves. Marfan's syndrome may represent a rare remaining contraindication for human AVR in children.
METHODS: The results of 100 consecutive pediatric AVRs (50 mechanical, 50 human) were reviewed.
RESULTS: There were five perioperative deaths in the mechanical group and one in the human group (p = 0.2). Late complications in the mechanical group included 4 late deaths, 2 cases of endocarditis, 3 thromboembolic complications, and 10 reoperations on the aortic valve. In the human group, there were no late deaths, 2 reoperations for allograft aortic valve deterioration (both in Marfan's patients), and 1 reoperation for allograft pulmonary valve stenosis. Four-year actuarial survival was 83% in the mechanical group and 98% in the human group (p = 0.02). Four-year actuarial survival free of all valve-related complications was 61% in the mechanical group and 88% in the human group (p = 0.008).
CONCLUSIONS: Human valves in children requiring AVR provide superior intermediate-term survival and freedom from valve-related complications compared to mechanical valves. Marfan's syndrome may represent a rare remaining contraindication for human AVR in children.
Предметные рубрики MeSH
Actuarial AnalysisAdolescentAdultAortic ValveBioprosthesisChildChild, PreschoolFemaleFollow-Up StudiesHeart Defects, CongenitalHeart Valve Prosthesis ImplantationHumansInfantMalePostoperative ComplicationsProsthesis FailureReoperationSurvival RateTransplantation, AutologousTransplantation, Homologous