Journal of child neurology · 2024
Seroprevalence of Lyme Disease in Children With Facial Nerve Palsy.
СтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод в очереди
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Murphy Bethany, Veras Julissa, Kolli Sindhura, Formanowski Brielle, Greenberg Patricia, Kleinman Lawrence, Malhotra Amisha, Bhise Vikram
Аннотация
This retrospective chart review examined children with documented Lyme disease serology in New Jersey aged <21 years presenting with facial nerve palsy. The presence of symptoms including tick bite, fever, headache, and arthritis was recorded. Data were categorized based on demographic factors, and multivariate regression was employed. We enrolled 122 children, 54% female (mean age of 11.4 ± 5.1 years); 22.1% had Lyme disease. Fever was a significant predictor of Lyme disease (P = .01), confirmed by multivariate regression (odds ratio [OR] = 16.11, 95% confidence interval [CI] = 2.04, 366.14), as was male gender (P = .01, OR = 3.68, 95% CI = 1.21, 12.89). This association held especially true in Lyme-endemic regions (prevalence ≥ 0.35). The combination of headache with fever was also significantly predictive (P = .01). We found no significant predictive value in the remaining symptoms. These findings suggest that clinical predictors may be useful in diagnosing Lyme disease and initiating early empiric treatment.