DOI 10.2807/1560-7917.es.2025.30.39.2500739

Медицинская библиотека · Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025

Early results from implementation of HIV pre-exposure prophylaxis (PrEP) with long-acting injectable cabotegravir for people with barriers to oral strategies, Italy, December 2024 to August 2025.

Moschese Davide, Esvan Rozenn, Fusetti Chiara, Barchi Virginia, Cossu Maria Vittoria, Giacinta Alessandro, Lazzarin Samuel, Terracini Giulia, Caruso Francesco, Micheli Giulia, Maddalena Donatella, Del Duca Giulia, Petri Francesco, Frate Gianluca, Matone Maddalena, Farinacci Damiano, Giacomelli Andrea, Faccendini Paolo, Visigalli Debora, Passacantilli Sara, Riva Agostino, Antinori Andrea, Gori Andrea, Mazzotta Valentina

СтатьяМногоцентровое исследованиеПеревод в очереди

Аннотация

Between December 2024 and August 2025, two Italian HIV/STI clinics offered long-acting injectable cabotegravir (CAB-LA) for HIV prevention in 265 individuals, representing the first European real-world implementation. Participants were prioritised based on vulnerabilities compromising oral pre-exposure prophylaxis (PrEP), such as poor adherence, comorbidities and behavioural barriers. Adherence to injections exceeded 95%, tolerability was favourable and only 1.5% discontinued for drug-related reasons. These findings demonstrate the feasibility of CAB-LA in European clinical services and support its use in specific populations.

Для цитирования: Moschese Davide, Esvan Rozenn, Fusetti Chiara, Barchi Virginia, Cossu Maria Vittoria, Giacinta Alessandro, Lazzarin Samuel, Terracini Giulia, Caruso Francesco, Micheli Giulia, Maddalena Donatella, Del Duca Giulia, Petri Francesco, Frate Gianluca, Matone Maddalena, Farinacci Damiano, Giacomelli Andrea, Faccendini Paolo, Visigalli Debora, Passacantilli Sara, Riva Agostino, Antinori Andrea, Gori Andrea, Mazzotta Valentina. Early results from implementation of HIV pre-exposure prophylaxis (PrEP) with long-acting injectable cabotegravir for people with barriers to oral strategies, Italy, December 2024 to August 2025.. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 2025. DOI: 10.2807/1560-7917.es.2025.30.39.2500739.

Предметные рубрики MeSH

Pre-Exposure Prophylaxis Pyridones Diketopiperazines HIV HIV Infections Italy HIV Integrase Inhibitors Humans Male Female Adult Middle Aged Injections, Intravenous Administration, Oral

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