[Evaluation of the assay of serum fructosamine in the surveillance of diabetes in children and adolescents].

Serum fructosamine and glycosylated haemoglobin were measured 4 times over 2 month period (1st, 15th, 30th and 60th days) in 40 young diabetics and in 26 controls. A positive correlation was found between these two parameters at the 15th, 30th and 60th days (0.44 less than r less than 0.61, P less than 0.01). There was a milder correlation between glycosylated haemoglobin and fasting glycemia (r = 0.43), between serum fructosamine and mean glycemia of the last 4 weeks (r = 0.38) and between serum fructosamine and 24 h glycosuria (r = 0.39) (P less than 0.05). Serum fructosamine, which reflects the mean glycemia of the last 3 weeks appears as a useful parameter in diabetic control, in association with glycosylated haemoglobin which reflects the mean glycemia of the last 2 months.