American journal on intellectual and developmental disabilities · 2018
Associations Between Medical History, Cognition, and Behavior in Youth With Down Syndrome: A Report From the Down Syndrome Cognition Project.
СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Rosser Tracie C, Edgin Jamie O, Capone George T, Hamilton Debra R, Allen Emily G, Dooley Kenneth J, Anand Payal, Strang John F, Armour A Chelsea, Frank-Crawford Michelle A, Channell Marie Moore, Pierpont Elizabeth I, Feingold Eleanor, Maslen Cheryl L, Reeves Roger H, Sherman Stephanie L
Аннотация
The cause of the high degree of variability in cognition and behavior among individuals with Down syndrome (DS) is unknown. We hypothesized that birth defects requiring surgery in the first years of life (congenital heart defects and gastrointestinal defects) might affect an individual's level of function. We used data from the first 234 individuals, age 6-25 years, enrolled in the Down Syndrome Cognition Project (DSCP) to test this hypothesis. Data were drawn from medical records, parent interviews, and a cognitive and behavior assessment battery. Results did not support our hypothesis. That is, we found no evidence that either birth defect was associated with poorer outcomes, adjusting for gender, race/ethnicity, and socioeconomic status. Implications for study design and measurement are discussed.