Asian Pacific journal of allergy and immunology · 2024
A case report of allergic bronchopulmonary mycosis caused by Alternaria alternata in colonization of Aspergillus.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Jo Min Ju, Yeo Yoomi, Min Kyueng-Whan, Chung Sung Jun, Park Tai Sun, Lee Hyun, Park Dong Won, Moon Ji-Yong, Sohn Jang Won, Kim Sang-Heon, Yoon Ho Joo, Kim Tae-Hyung
Аннотация
BACKGROUND: Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease caused by a complex hypersensitivity reaction to colonization of the airways with various fungi. ABPA caused by Alternaria alternata, other than Aspergillus spp., is named Allergic bronchopulmonary mycosis (ABPM).
OBJECTIVE: To describe the first case of ABPM caused by Alternaria alternata in East Asia.
METHODS: Case report.
RESULTS: A 58-year-old female visited our hospital due to an abnormal chest x-ray, following chest computed tomography (CT) revealed consolidation in the left lower lobe. On laboratory finding, eosinophil count and total IgE level were high. The skin prick test and specific IgE for Alternaria alternata were positive. After diagnosis of ABPM, the patient was treated with prednisolone without antifungal agents, and her chest image was much improved.
CONCLUSIONS: Aspergillus is most common etiology of allergic pulmonary disease, however, Alternaria should be considered even though positive culture of Aspergillus spp.
OBJECTIVE: To describe the first case of ABPM caused by Alternaria alternata in East Asia.
METHODS: Case report.
RESULTS: A 58-year-old female visited our hospital due to an abnormal chest x-ray, following chest computed tomography (CT) revealed consolidation in the left lower lobe. On laboratory finding, eosinophil count and total IgE level were high. The skin prick test and specific IgE for Alternaria alternata were positive. After diagnosis of ABPM, the patient was treated with prednisolone without antifungal agents, and her chest image was much improved.
CONCLUSIONS: Aspergillus is most common etiology of allergic pulmonary disease, however, Alternaria should be considered even though positive culture of Aspergillus spp.