Twin gestation induced by clomiphene citrate and bromocriptine in both horns of a bicornuate uterus.

OBJECTIVE

To describe a case of twin gestation that occurred in both horns of a bicornuate uterus after the administration of clomiphene citrate and bromocriptine.

DESIGN

Case report.

SETTING

Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Korea.

PATIENT(S): A 34-year-old woman presented with secondary infertility and hyperprolactinemia.

INTERVENTION(S): Bromocriptine, 2.5 mg/day, was administered immediately, and clomiphene citrate, 150 mg/day, was started from menstruation day 5 for 5 days.

MAIN OUTCOME MEASURE(S): The establishment of pregnancy and obstetric outcome.

RESULT(S): A nonidentical twin pregnancy occurred but ended in preterm delivery at 24 weeks. One baby has survived for over 3 months.

CONCLUSION(S): Twin gestation can occur in both horns of a bicornuate uterus after clomiphene citrate administration.