Critical care medicine · 2025
Experiencing Sepsis: A Meta-Ethnography.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Sim Johnston Marie W, Lorimer Amy J, Haines Kimberley J, Litton Edward
Аннотация
OBJECTIVE: To explore and synthesize the adverse and transformative experiences of sepsis survivors and their caregivers, to generate novel, experience-based insights that inform recovery support and future care strategies.
DATA SOURCES: Five databases (MEDLINE, Embase, CINAHL, PsycINFO, Web of Science) were searched from 2000 to 2025.
STUDY SELECTION: Eligible studies included qualitative or mixed-methods research reporting experiences of adult sepsis survivors and/or caregivers. Studies focusing solely on healthcare providers or published in languages other than English were excluded. Nine studies met inclusion criteria.
DATA EXTRACTION: First- and second-order constructs were extracted. Study quality was assessed using the Critical Appraisal Skills program. Confidence in findings was evaluated using GRADE-Confidence in Evidence from Reviews of Qualitative Research, which assesses methodological limitations, coherence, adequacy, and relevance.
DATA SYNTHESIS: A meta-ethnographic approach guided synthesis, using Noblit and Hare's seven-phase methodology. Five third-order themes emerged for survivors: 1) increased dependency (moderate confidence); 2) ICU fog (high confidence); 3) psychological adjustment (moderate confidence); 4) gratitude and guilt in relationships (moderate confidence); and 5) post-discharge challenges (moderate confidence). Three themes emerged for caregivers: 1) adapting to caregiving (moderate confidence); 2) uncertainty about the future (moderate confidence); and 3) communication challenges (low confidence).Experiences were shaped by both adversity and transformation. Dependency emerged as a central theme influencing autonomy, identity, and engagement with healthcare. Caregivers experienced emotional and logistical strain, often unsupported.
CONCLUSIONS: Although deeply personal, sepsis survivorship is marked by consistent themes. Survivor experiences reveal critical insights and generate directions for research and intervention. Findings underscore the need to strengthen survivorship care by prioritizing psychological support, effective communication, and responsive post-discharge services.
DATA SOURCES: Five databases (MEDLINE, Embase, CINAHL, PsycINFO, Web of Science) were searched from 2000 to 2025.
STUDY SELECTION: Eligible studies included qualitative or mixed-methods research reporting experiences of adult sepsis survivors and/or caregivers. Studies focusing solely on healthcare providers or published in languages other than English were excluded. Nine studies met inclusion criteria.
DATA EXTRACTION: First- and second-order constructs were extracted. Study quality was assessed using the Critical Appraisal Skills program. Confidence in findings was evaluated using GRADE-Confidence in Evidence from Reviews of Qualitative Research, which assesses methodological limitations, coherence, adequacy, and relevance.
DATA SYNTHESIS: A meta-ethnographic approach guided synthesis, using Noblit and Hare's seven-phase methodology. Five third-order themes emerged for survivors: 1) increased dependency (moderate confidence); 2) ICU fog (high confidence); 3) psychological adjustment (moderate confidence); 4) gratitude and guilt in relationships (moderate confidence); and 5) post-discharge challenges (moderate confidence). Three themes emerged for caregivers: 1) adapting to caregiving (moderate confidence); 2) uncertainty about the future (moderate confidence); and 3) communication challenges (low confidence).Experiences were shaped by both adversity and transformation. Dependency emerged as a central theme influencing autonomy, identity, and engagement with healthcare. Caregivers experienced emotional and logistical strain, often unsupported.
CONCLUSIONS: Although deeply personal, sepsis survivorship is marked by consistent themes. Survivor experiences reveal critical insights and generate directions for research and intervention. Findings underscore the need to strengthen survivorship care by prioritizing psychological support, effective communication, and responsive post-discharge services.