Comparison of Cerebral Saturation and Brain Net Water Uptake After Moderate Traumatic Brain Injury.

UNLABELLED: The aim was to study the relationship between net water uptake (NWU) and cerebral oxygenation in patients with posttraumatic ischaemia (PTI) foci after moderate traumatic brain injury (moTBI).

MATERIALS AND

METHODS

Perfusion computed tomography (PCT) was performed for 72 patients with PTI foci after moTBI in 2013-2022. The mean age of the patients was 32.7 ± 12.5 years (from 18 to 65 years), 25 women and 47 men. Cerebral tissue oxygen saturation (SctO2) was evaluated using Fore-Sight 2030 (CAS Medical Systems Inc., USA) in the region of the frontal lobe pole (FLP). NWU was calculated from non-contrast CT. Data are shown as a median [interquartile range]. P < 0.05 was considered statistically significant.

RESULTS

SctO2 in FLP varied within the range from 61% to 88%. It was 62% [55.4;72.1] over the lesion frontal lobe with PTI and 64% [58.5;73.7] over the opposite FLP side. The average NWU in the FLP cortex on the PTI side was 4.98% [2.21;7.39]. In the case when there were no focal injuries in the frontal lobes, SctO2 was significantly correlated with higher NWU (R = -0.780, p < 0.00001).

CONCLUSIONS

The cerebral oxygen tissue saturation correlates with net water uptake in patients with PTI after moTBI (p < 0.005).