Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 1997
Pulmonary hemosiderosis with hypersensitivity to buckwheat.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Agata H, Kondo N, Fukutomi O, Takemura M, Tashita H, Kobayashi Y, Shinoda S, Nishida T, Shinbara M, Orii T
Аннотация
BACKGROUND: Adverse reactions after ingesting buckwheat are known to be IgE-mediated. Further, hypersensitivity reactions may be involved in some patients with pulmonary hemosiderosis related to cow milk sensitivity. We, however, encountered a patient with pulmonary hemosiderosis related to buckwheat protein without high levels of buckwheat-specific IgE antibodies.
OBJECTIVE: The aim of this study was to investigate the mechanisms.
METHODS: RAST for anti-buckwheat IgE, skin prick test, skin patch test, and proliferative responses of peripheral blood mononuclear cells to buckwheat were investigated in this patient.
RESULTS: RAST values for buckwheat protein were negative, and skin prick test for buckwheat protein also gave negative results. On the other hand, skin patch testing for buckwheat protein elicited positive responses. Further, peripheral blood mononuclear cells of our patient responded to buckwheat protein.
CONCLUSIONS: Our patient had pulmonary hemosiderosis related to non-immediate buckwheat protein hypersensitivity.
OBJECTIVE: The aim of this study was to investigate the mechanisms.
METHODS: RAST for anti-buckwheat IgE, skin prick test, skin patch test, and proliferative responses of peripheral blood mononuclear cells to buckwheat were investigated in this patient.
RESULTS: RAST values for buckwheat protein were negative, and skin prick test for buckwheat protein also gave negative results. On the other hand, skin patch testing for buckwheat protein elicited positive responses. Further, peripheral blood mononuclear cells of our patient responded to buckwheat protein.
CONCLUSIONS: Our patient had pulmonary hemosiderosis related to non-immediate buckwheat protein hypersensitivity.