Atopic dermatitis in 15q24 microdeletion syndrome: a social media study.

BACKGROUND

Chromosome 15q24 microdeletion is a rare genetic disorder, and the skin manifestations are poorly documented.

OBJECTIVES

In this cross-sectional observational study using social media (Facebook), we investigated the prevalence of atopic dermatitis in 15q24 microdeletion syndrome.

MATERIALS &

METHODS

Parents and caregivers of a child with the syndrome were asked to participate using a validated self-reporting questionnaire.

RESULTS

In total, 60 participants completed the questionnaire. The prevalence of atopic dermatitis was 35% among patients with chromosome 15q24 deletion. Few patients received treatment according to international guidelines.

CONCLUSION

We describe the largest cohort of patients with 15q24 microdeletion syndrome, revealing a high prevalence of atopic dermatitis. Patients with 15q24 microdeletion syndrome should undergo dermatological evaluation for screening and management of atopic dermatitis. Approaching individuals via social media is a successful strategy, resulting in good information which may be used to counsel families.