Journal of occupational and environmental medicine · 2012
Mortality among population with exposure to industrial air pollution containing nickel and other toxic metals.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Pasanen Kari, Pukkala Eero, Turunen Anu W, Patama Toni, Jussila Ilkka, Makkonen Sari, Salonen Raimo O, Verkasalo Pia K
Аннотация
OBJECTIVE: To assess disease mortality among people with exposure to metal-rich particulate air pollution.
METHODS: We conducted a cohort study on mortality from 1981 to 2005 among 33,573 people living near a nickel/copper smelter in Harjavalta, Finland. Nickel concentration in soil humus was selected as an indicator for long-term exposure. Relative risks--adjusted for age, socioeconomic status, and calendar period--were calculated for three exposure zones.
RESULTS: The relative risks for diseases of the circulatory system by increasing exposure were 0.93 (95% confidence interval = 0.79 to 1.09), 1.20 (1.04 to 1.39), and 1.18 (1.00 to 1.39) among men and 1.01 (0.88 to 1.17), 1.20 (1.04 to 1.38), and 1.14 (0.97 to 1.33) among women. Exclusion of smelter workers from the cohort did not materially change the results.
CONCLUSIONS: Long-term environmental exposure to metal-rich air pollution was associated with increased mortality from circulatory diseases.
METHODS: We conducted a cohort study on mortality from 1981 to 2005 among 33,573 people living near a nickel/copper smelter in Harjavalta, Finland. Nickel concentration in soil humus was selected as an indicator for long-term exposure. Relative risks--adjusted for age, socioeconomic status, and calendar period--were calculated for three exposure zones.
RESULTS: The relative risks for diseases of the circulatory system by increasing exposure were 0.93 (95% confidence interval = 0.79 to 1.09), 1.20 (1.04 to 1.39), and 1.18 (1.00 to 1.39) among men and 1.01 (0.88 to 1.17), 1.20 (1.04 to 1.38), and 1.14 (0.97 to 1.33) among women. Exclusion of smelter workers from the cohort did not materially change the results.
CONCLUSIONS: Long-term environmental exposure to metal-rich air pollution was associated with increased mortality from circulatory diseases.
Предметные рубрики MeSH
AdolescentAdultAgedAged, 80 and overAir PollutantsAlzheimer DiseaseCardiovascular DiseasesChildChild, PreschoolCopperDiabetes MellitusEnvironmental ExposureFemaleFinlandFollow-Up StudiesHumansInfantMaleMetallurgyMiddle AgedNickelParticulate MatterRespiratory Tract DiseasesRespiratory Tract NeoplasmsTime FactorsYoung Adult