Emerging infectious diseases · 2025
Spotted Fever Group Rickettsioses among Hospitalized Patients and Circulation of Rickettsia in Ticks, Kazakhstan, 2019.
СтатьяНазвание и аннотация: Перевод в очереди
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Bumburidi Yekaterina V, Berezovskiy Dmitriy V, Zhakipbayeva Bakhytkul T, Horth Roberta Z, Millman Alexander J, Nicholson William L, Zemtsova Galina E, Seffren Victoria, Maltseva Elina R, Berdygulova Zhanna A, Ostapchuk Yekaterina O, Perfilyeva Yuliya V, Dmitrovskiy Andrey M, Dukayeva Zhansulu K, Shapiyeva Zhanna Zh
Аннотация
Testing for spotted fever group rickettsioses (SFGR) and the criteria for identifying suspected patients are not routinely used in Kazakhstan. In 2019, we performed a cross-sectional study in 6 sentinel hospitals in the Pavlodar region. We tested 105 hospitalized patients with SFGR-like symptoms by using PCR or indirect immunofluorescence antibody assay and identified 62 cases of SFGR. Most (78%) cases of disease were caused by Rickettsia sibirica and R. raoultii. Cutaneous signs (eschar or rash) were found in 87% of SFGR patients; 79% had a rash, 48% had an eschar, and 13% had neither. Testing of suspected rickettsia cases resulted in a 27% increase in laboratory-detected SFGR over the mean of the previous 3 years (62 vs. 49). Broadening the case definition by including fever, headache, or myalgia and expanding routine testing for suspected cases of SFGR could contribute to improved case detection and earlier treatment.