Expert opinion on drug delivery · 2020
Cell-laden alginate hydrogels for the treatment of diabetes.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Izeia Lukin, Eufrasio-da-Silva Tatiane, Dolatshahi-Pirouz Alireza, Ostrovidov Serge, Paolone Giovanna, Peppas Nicholas A, De Vos Paul, Emerich Dwaine, Orive Gorka
Аннотация
INTRODUCTION: Diabetes mellitus is an ever-increasing medical condition that currently suffers 1 of 11 adults who may have lifelong commitment with insulin injections. Cell-laden hydrogels releasing insulin may provide the ultimate means of correcting diabetes. Here, we provide insights of this cell-based approach including latest preclinical and clinical progress both from academia and industry.
AREA COVERED: The present article focuses on reviewing latest advances in cell-laden hydrogels both from the technological and biological perspective. The most relevant clinical results including clinical trials are also discussed.
EXPERT OPINION: Current progress in technological issues (stem cells, devices, biomaterials) have contributed cell encapsulation science to have a very relevant progress in the field of diabetes treatment.
AREA COVERED: The present article focuses on reviewing latest advances in cell-laden hydrogels both from the technological and biological perspective. The most relevant clinical results including clinical trials are also discussed.
EXPERT OPINION: Current progress in technological issues (stem cells, devices, biomaterials) have contributed cell encapsulation science to have a very relevant progress in the field of diabetes treatment.