Indian pediatrics · 2016
Prolonged Infusion of Dexmedetomidine in Critically-ill Children.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Andreolio Cinara, Piva Jefferson Pedro, Baldasso Elisa, Ferlini Roberta, Piccoli Rafaela
Аннотация
OBJECTIVE: To describe main indications, doses, length of infusion and side effects related to dexmedetomidine infusion.
METHODS: Observational and retrospective study evaluating dexmedetomidine use in pediatric intensive care unit.
RESULTS: 77 children received dexmedetomidine infusion longer than 6 hours for mechanical ventilation weaning (32.5%), post- neurosurgery and post-upper airway surgery (24.7%), non-invasive ventilation (13%), refractory tachycardia (6.5%) and other causes (23.3%). After 6 hours of infusion, significant decrease in mean arterial pressure and heart rate was observed in all groups. Six children (8%) required withdrawal of drug because of possible side effects: hypotension, bradycardia and somnolence.
CONCLUSION: Dexmedetomidine may be used as sedative in critically ill children without much side effects.
METHODS: Observational and retrospective study evaluating dexmedetomidine use in pediatric intensive care unit.
RESULTS: 77 children received dexmedetomidine infusion longer than 6 hours for mechanical ventilation weaning (32.5%), post- neurosurgery and post-upper airway surgery (24.7%), non-invasive ventilation (13%), refractory tachycardia (6.5%) and other causes (23.3%). After 6 hours of infusion, significant decrease in mean arterial pressure and heart rate was observed in all groups. Six children (8%) required withdrawal of drug because of possible side effects: hypotension, bradycardia and somnolence.
CONCLUSION: Dexmedetomidine may be used as sedative in critically ill children without much side effects.