Design of Low-Wear and Self-Recoverable Polyurethane Elastomers via Microphase Separation and Dynamic Bonding for Artificial Meniscus Prostheses.

High-performance materials for artificial meniscus prostheses currently exhibit notable limitations in wear resistance, failing to fully adapt to the complex physiological microenvironment of the human body. Polyurethane elastomers have emerged as highly promising candidate materials in the biomedical field, attributed to their tunable mechanical properties and facile processability. In this study, a low-wear, self-healing polyurethane elastomer (PPU1.0) for artificial meniscus prostheses is developed through the synergistic optimization of microphase separation and dynamic hydrazone bonds. PPU1.0 achieved significantly reduced friction, with an average coefficient of friction (ACOF) of 0.06578, alongside rapid self-recovery performance through precisely controlling the isocyanate index (R = 4.5) and the density of the hydrazone bond derived from perillaldehyde.