Microemulsion Mediated Synthesis and Characterization of CdS Nanoparticles and Its Anti-Biofilm Efficacy Against Escherichia Coli ATCC 25922.

In this paper, we have reported the synthesize of CdS Nanoparticles through microemulsion mediated Triton X-100 neutral micelles at room temperature and its anti-biofilm activity against Escherichia coli. The encapsulated micelles nanoparticle system was studied for its absorption at 450 nm and emission spectrum was recorded peaking at 402 and 425 nm excited at 350 nm. The X-ray diffractive pattern (XRD) was confirmed the presence of cubic CdS crystallites. High resolution Transmission electron microscopy (HRTEM) reveals that the particles were spherical in shape and average size is 20 nm. Anti-biofilm activity of CdS nanoparticles were studied at 5 μL and inhibition of growth of biofilm formed by Escherichia coli bacteria was documented by confocal laser scanning microscopy(CLSM) and confirmed that CdS nanoparticles in low concentration have very good anti-biofilm activity and hence may be used in antibacterial drug formulation.