BJOG : an international journal of obstetrics and gynaecology · 2013
Cost-effectiveness of induction of labour at term with a Foley catheter compared to vaginal prostaglandin E₂ gel (PROBAAT trial).
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
van Baaren G J, Jozwiak M, Opmeer B C, Oude Rengerink K, Benthem M, Dijksterhuis M G K, van Huizen M E, van der Salm P C M, Schuitemaker N W E, Papatsonis D N M, Perquin D A M, Porath M, van der Post J A M, Rijnders R J P, Scheepers H C J, Spaanderman M, van Pampus M G, de Leeuw J W, Mol B W J, Bloemenkamp K W M
Аннотация
OBJECTIVE: To assess the economic consequences of labour induction with Foley catheter compared to prostaglandin E2 gel.
DESIGN: Economic evaluation alongside a randomised controlled trial.
SETTING: Obstetric departments of one university and 11 teaching hospitals in the Netherlands.
POPULATION: Women scheduled for labour induction with a singleton pregnancy in cephalic presentation at term, intact membranes and an unfavourable cervix; and without previous caesarean section.
METHODS: Cost-effectiveness analysis from a hospital perspective.
MAIN OUTCOME MEASURES: We estimated direct medical costs associated with healthcare utilisation from randomisation to 6 weeks postpartum. For caesarean section rate, and maternal and neonatal morbidity we calculated the incremental cost-effectiveness ratios, which represent the costs to prevent one of these adverse outcomes.
RESULTS: Mean costs per woman in the Foley catheter group (n = 411) and in the prostaglandin E₂ gel group (n = 408), were €3297 versus €3075, respectively, with an average difference of €222 (95% confidence interval -€157 to €633). In the Foley catheter group we observed higher costs due to longer labour ward occupation and less cost related to induction material and neonatal admissions. Foley catheter induction showed a comparable caesarean section rate compared with prostaglandin induction, therefore the incremental cost-effectiveness ratio was not informative. Foley induction resulted in fewer neonatal admissions (incremental cost-effectiveness ratio €2708) and asphyxia/postpartum haemorrhage (incremental cost-effectiveness ratios €5257) compared with prostaglandin induction.
CONCLUSIONS: Foley catheter and prostaglandin E2 labour induction generate comparable costs.
DESIGN: Economic evaluation alongside a randomised controlled trial.
SETTING: Obstetric departments of one university and 11 teaching hospitals in the Netherlands.
POPULATION: Women scheduled for labour induction with a singleton pregnancy in cephalic presentation at term, intact membranes and an unfavourable cervix; and without previous caesarean section.
METHODS: Cost-effectiveness analysis from a hospital perspective.
MAIN OUTCOME MEASURES: We estimated direct medical costs associated with healthcare utilisation from randomisation to 6 weeks postpartum. For caesarean section rate, and maternal and neonatal morbidity we calculated the incremental cost-effectiveness ratios, which represent the costs to prevent one of these adverse outcomes.
RESULTS: Mean costs per woman in the Foley catheter group (n = 411) and in the prostaglandin E₂ gel group (n = 408), were €3297 versus €3075, respectively, with an average difference of €222 (95% confidence interval -€157 to €633). In the Foley catheter group we observed higher costs due to longer labour ward occupation and less cost related to induction material and neonatal admissions. Foley catheter induction showed a comparable caesarean section rate compared with prostaglandin induction, therefore the incremental cost-effectiveness ratio was not informative. Foley induction resulted in fewer neonatal admissions (incremental cost-effectiveness ratio €2708) and asphyxia/postpartum haemorrhage (incremental cost-effectiveness ratios €5257) compared with prostaglandin induction.
CONCLUSIONS: Foley catheter and prostaglandin E2 labour induction generate comparable costs.