JAMA neurology · 2018
The Changing Landscape of Pediatric Migraine Therapy: A Review.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Patterson-Gentile Carlyn, Szperka Christina L
Аннотация
IMPORTANCE: Migraine is a disabling and prevalent condition that affects the pediatric and adolescent population. This review describes current acute and preventive migraine pharmacologic therapies for the pediatric and adolescent population.
OBSERVATIONS: Multiple pharmacotherapies that have been used in the treatment of acute headache and prevention in pediatric migraine are reviewed. There have been recent advances in the management of migraines among pediatric and adolescent patients, including US Food and Drug Administration approval of triptans for acute management in children as young as 6 years, and the first prospective, randomized, double-blind, placebo-controlled comparative study of preventive pharmacotherapy in pediatric migraine. A major challenge of evidence-based research in pediatric and adolescent migraine is the significant placebo effect.
CONCLUSIONS AND RELEVANCE: Although progress is being made in the management of migraines among pediatric and adolescent patients, there remains much work to be done.
OBSERVATIONS: Multiple pharmacotherapies that have been used in the treatment of acute headache and prevention in pediatric migraine are reviewed. There have been recent advances in the management of migraines among pediatric and adolescent patients, including US Food and Drug Administration approval of triptans for acute management in children as young as 6 years, and the first prospective, randomized, double-blind, placebo-controlled comparative study of preventive pharmacotherapy in pediatric migraine. A major challenge of evidence-based research in pediatric and adolescent migraine is the significant placebo effect.
CONCLUSIONS AND RELEVANCE: Although progress is being made in the management of migraines among pediatric and adolescent patients, there remains much work to be done.
Предметные рубрики MeSH
AdolescentAdrenergic beta-AntagonistsAmitriptylineAnalgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalAnticonvulsantsCalcium Channel BlockersChildCognitive Behavioral TherapyDihydroergotamineDopamine AntagonistsFluid TherapyGlucocorticoidsHeadache Disorders, SecondaryHumansMagnesiumMigraine DisordersNerve BlockTopiramateTryptaminesValproic Acid