Challenges in the final stage of polio eradication.

India and many other countries of the world have supported the resolution taken by the World Health Organization (WHO) in 1988 to eradicate poliomyelitis globally by the year 2000. At the beginning of 2002, there were 10 countries in the world with endemic transmission. India included in the high transmission area. WHO is preparing guidelines on the program response (both immunization and surveillance) to wild poliovirus isolation from the environment. This technology will be useful in monitoring the disappearance of vaccine virus after ceasing OPV vaccination.