Postgraduate medical journal · 2025
Blood biomarkers of Alzheimer's disease: findings from proteomics.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wang Yuye, Niu Xiaoqian, Zhen Weizhe, Zhang Bin, Chen Leian, Liu Yuchen, Sun Wei, Peng Dantao
Аннотация
BACKGROUND: Alzheimer's disease, the most prevalent cause of dementia, is a worldwide health problem. Proteomics is the systematic study of proteins and peptides to provide comprehensive descriptions. Aiming to obtain a more accurate and convenient clinical diagnosis, researchers are working on blood biomarkers.
METHOD: This review synthesizes findings from previous studies investigating blood biomarkers for Alzheimer's disease using proteomic approaches.
RESULTS: We summarized the application of blood proteomics as diagnostic biomarkers and associations with clinical indicators such as neuropsychological performances, Aβ deposition and brain atrophy in Alzheimer's disease, and mild cognitive impairment.
CONCLUSION: In summary, blood proteomics is suggested to be promising in biomarkers of Alzheimer's disease.
METHOD: This review synthesizes findings from previous studies investigating blood biomarkers for Alzheimer's disease using proteomic approaches.
RESULTS: We summarized the application of blood proteomics as diagnostic biomarkers and associations with clinical indicators such as neuropsychological performances, Aβ deposition and brain atrophy in Alzheimer's disease, and mild cognitive impairment.
CONCLUSION: In summary, blood proteomics is suggested to be promising in biomarkers of Alzheimer's disease.