Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 1995
Continuous epidural morphine/butorphanol infusion following selective dorsal rhizotomy in children.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Lawhorn C D, Boop F A, Brown R E, Andelman P D, Schmitz M L, Kymer P J, Shirey R
Аннотация
The authors prospectively evaluated 15 patients who had undergone selective dorsal rhizotomy who were given a continuous morphine/butorphanol infusion, to determine whether variations in the postoperative pain control and side effects seen using a bolus technique could be reduced. Patients had an epidural catheter placed at the end of the operative procedure through which 50-60 micrograms/kg preservative-free morphine and 15-20 micrograms/kg butorphanol was administered. A continuous epidural infusion of 5 micrograms/kg h morphine and 1.2 micrograms/kg h butorphanol was then initiated. Postoperatively, mean pain scores were excellent. No patient required additional systemic analgesics during the 72-h investigational period. A low incidence of nausea, and no vomiting, pruritus, or respiratory depression was reported by the cohort. All patients maintained oxygen saturations above 95%. This indicates that the use of a continuous epidural infusion provides excellent pain control, decreases the occurrence of untoward side effects, and allows the early initiation of occupational and physical therapy postoperatively.