[Micromycetes extracellular proteinases with fibrinolytic and anticoagulant properties].

One hundred and sixteen strains of microscopic fungal belonging to different taxonomic groups were tested for their ability ti synthesize extracellular proteinases with caseinolytic, fibrinolytic, plasminogen activator-like, and anticoagulant (prolonging the partial thromboplastin time) activities. Several producers of anticoagulants prolonging the partial thromboplastin time, probably via the activation of the protein C system, were revealed. The effectiveness of the fungal anticoagulants was close to that of the protein C activators from Agkistrodon snake venom.