Computer tomographic densohistogramic characteristic of the renal cortex in children with suspected autosomal dominant polycystic kidney disease.

Computertomographic densohistogramic analysis of the renal cortex was performed on 36 children aged seven to 19. The clinicogenealogical and echographic findings suggest the presence of autosomal dominant polycystic kidney disease (ADPKD). Diagnoses made on the basis of two methods (echography and computer tomography) coincided in only 46.15 percent of examined cases. Histogramic analysis confirmed the echographic diagnosis of ADPKD in 38.46 percent of the remaining cases while it rejected the ADPKD diagnosis in 15.39 percent. Computer tomographic densohistogramic analysis is recommended for children when echographic findings suggest the presence of ADPKD. It allows early detection of the disease, effective medical surveillance and prophylaxis of complications.