Radiology · 2001
Intramedullary osteosclerosis: imaging features in nine patients.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Chanchairujira K, Chung C B, Lai Y M, Haghighi P, Resnick D
Аннотация
PURPOSE: To determine the conventional radiographic, computed tomographic (CT), magnetic resonance (MR) imaging, scintigraphic, and histologic features of intramedullary osteosclerosis and to review the clinical features.
MATERIALS AND METHODS: Nine female patients with leg pain and imaging features indicative of intramedullary sclerosis were seen during a 25-year period. None of the patients had a history of trauma or infection, familial bone disease, or related abnormal laboratory findings. Imaging studies included radiography (n = 9), CT (n = 4), MR imaging (n = 5), and skeletal scintigraphy (n = 5). Histologic correlation was available in five patients.
RESULTS: Sixteen bone lesions (midtibia, n = 14; distal fibula, n = 1; and proximal femur, n = 1) were evident. Both lower extremities were involved in seven patients, and a single extremity was involved in two. Intramedullary sclerosis was present, as was cortical thickening, mainly in the diaphysis of the long bones, without extensive periosteal reaction or soft-tissue involvement. Findings at bone scintigraphy were positive in all lesions. Histologic analysis showed nonspecific changes of markedly sclerotic bone with a variable degree of mineralization and maturity.
CONCLUSION: Intramedullary osteosclerosis is a distinct disorder that typically affects the diaphysis of one or both tibiae in women. Characteristic imaging findings, when coupled with clinical information, allow precise diagnosis.
MATERIALS AND METHODS: Nine female patients with leg pain and imaging features indicative of intramedullary sclerosis were seen during a 25-year period. None of the patients had a history of trauma or infection, familial bone disease, or related abnormal laboratory findings. Imaging studies included radiography (n = 9), CT (n = 4), MR imaging (n = 5), and skeletal scintigraphy (n = 5). Histologic correlation was available in five patients.
RESULTS: Sixteen bone lesions (midtibia, n = 14; distal fibula, n = 1; and proximal femur, n = 1) were evident. Both lower extremities were involved in seven patients, and a single extremity was involved in two. Intramedullary sclerosis was present, as was cortical thickening, mainly in the diaphysis of the long bones, without extensive periosteal reaction or soft-tissue involvement. Findings at bone scintigraphy were positive in all lesions. Histologic analysis showed nonspecific changes of markedly sclerotic bone with a variable degree of mineralization and maturity.
CONCLUSION: Intramedullary osteosclerosis is a distinct disorder that typically affects the diaphysis of one or both tibiae in women. Characteristic imaging findings, when coupled with clinical information, allow precise diagnosis.