Archives of disease in childhood · 2009
Transient renal insufficiency following dipyrone overdose.
СтатьяНазвание и аннотация: Перевод в очереди
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Abu-Kishk Ibrahim, Goldman Michael, Mordish Yair, Berkovitch Matitiahu, Kozer Eran
Аннотация
AIM: To describe the incidence of acute renal insufficiency after dipyrone overdose in children.
METHODS: The medical records of all patients < or =18 years of age during a 3-year period presenting at Assaf Harofeh Medical Center due to toxic exposure were retrospectively reviewed. Patients suffering from dipyrone overdose were compared with all the other patients.
RESULTS: 235 cases were included in the final analysis. Of these, 26 (11%) patients were exposed to dipyrone (median age 15 years). Three of the 26 patients (12%) had transient non-oliguric renal insufficiency. One other patient who did not receive dipyrone also developed transient renal insufficiency.
CONCLUSIONS: Dipyrone overdose is frequent and may cause acute non-oliguric renal insufficiency. Renal function should be monitored in such patients.
METHODS: The medical records of all patients < or =18 years of age during a 3-year period presenting at Assaf Harofeh Medical Center due to toxic exposure were retrospectively reviewed. Patients suffering from dipyrone overdose were compared with all the other patients.
RESULTS: 235 cases were included in the final analysis. Of these, 26 (11%) patients were exposed to dipyrone (median age 15 years). Three of the 26 patients (12%) had transient non-oliguric renal insufficiency. One other patient who did not receive dipyrone also developed transient renal insufficiency.
CONCLUSIONS: Dipyrone overdose is frequent and may cause acute non-oliguric renal insufficiency. Renal function should be monitored in such patients.