Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) associated with normal-pressure hydrocephalus Anatomoclinical report of one case.

The occurrence of two different dementing diseases, Creutzfeldt-Jakob disease and normal-pressure hydrocephalus in a single patient is described. The inefficacy of a shunt procedure in this particular case, and the need of a brain biopsy in patients with normal-pressure hydrocephalus before undergoing cerebrospinal fluid shunting are stressed. A purely coincidental occurrence, or a possible aetiopathogenic relationship between both diseases are postulated.