Radionuclide imaging in primary amyloidosis with liver involvement.

A 74-year-old man with hepatomegaly, hyperglycemia, and proteinuria was diagnosed with primary amyloidosis with liver involvement, proven by biopsy. Abnormal distribution of tracer in the liver on Tc-99m phytate liver-spleen imaging and abnormal tracer uptake by the liver on Tc-99m pyrophosphate whole body imaging were observed. Scintigraphic imaging studies may be used noninvasively to evaluate the involvement of organs in patients with primary amyloidosis, reducing the risk of bleeding caused by biopsy.