Oral and maxillofacial surgery · 2010
Recombinant human bone morphogenetic protein-2 (rhBMP-2) in the treatment of mandibular sequelae after tumor resection.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Zétola André, Ferreira Felipe Mussi, Larson Rafaela, Shibli Jamil Awad
Аннотация
BACKGROUND: Ameloblastoma is a locally aggressive tumor most often found in posterior body and angle of the mandible. Although ameloblastoma has histological characteristics of benignity, they have a high percentage of local recurrence and possible malignant development if treated improperly.
CASE REPORT: This report presents a treatment of unusual mandibular sequelae after tumor resection using recombinant human bone morphogenetic protein-2 (rhBMP-2) associated with hydroxyapatite (HA) and calcium triphosphate (TCP).
DISCUSSION: Seven months after surgery, the patient was asymptomatic, with stable occlusion and class I, without signs of infection or rejection, and bone repair with rigidity compatible to an immature bone structure was observed. Reconstruction of large mandibular bone defect with a combination of rhBMP-2 and HA/TCP achieving a satisfactory result with less invasive and minimum morbidity has been demonstrated.
CASE REPORT: This report presents a treatment of unusual mandibular sequelae after tumor resection using recombinant human bone morphogenetic protein-2 (rhBMP-2) associated with hydroxyapatite (HA) and calcium triphosphate (TCP).
DISCUSSION: Seven months after surgery, the patient was asymptomatic, with stable occlusion and class I, without signs of infection or rejection, and bone repair with rigidity compatible to an immature bone structure was observed. Reconstruction of large mandibular bone defect with a combination of rhBMP-2 and HA/TCP achieving a satisfactory result with less invasive and minimum morbidity has been demonstrated.
Предметные рубрики MeSH
AdultAmeloblastomaBiocompatible MaterialsBone Morphogenetic Protein 2Bone PlatesBone SubstitutesBone TransplantationCalcium PhosphatesCollagenCutaneous FistulaDevice RemovalDrug CarriersDurapatiteEquipment FailureFemaleFollow-Up StudiesHumansMandibular NeoplasmsOral FistulaRecombinant ProteinsPlastic Surgery ProceduresSurgical MeshSurgical Wound DehiscenceSurgical Wound InfectionTransforming Growth Factor beta