The impacts of transcatheter occlusion for congenital atrial septal defect on atrial volume, function, and synchronicity in children: a three-dimensional echocardiography study.

OBJECTIVE

To evaluate the impacts of transcatheter closure for atrial septal defect (ASD) on the atria.

METHODS

Thirty-four patients with ASD undergoing transcatheter occlusion were recruited in the study, and 34 patients undergoing surgical operation and 34 healthy children were age-matched as controls. A real time three-dimensional (RT3DE) echocardiography was used to measure the volume, function, and synchronicity of the atria.

RESULTS

There was no difference in the atrial volume and function between the transcatheter occlusion group and healthy control group (P > 0.05). However, the parameters reflecting the atrial asynchrony were larger in the transcatheter occlusion group (P < 0.05). Compared to the surgical repair group, the transcatheter occlusion group had smaller maximum volume of the left atrium (21.0 +/- 5.2 ml/m(2) vs 24.3 +/- 5.8 ml/m(2), P = 0.01), smaller total emptying volume of the left atrium (12.7 +/- 4.3 ml/m(2) vs 15.1 +/- 3.8 ml/m(2), P = 0.014), smaller total emptying volume of the right atrium (13.5 +/- 5.2 ml/m(2) vs 16.1 +/- 4.7 ml/m(2), P = 0.029), and larger atrial systolic asynchrony indices.

CONCLUSIONS

An atrial asynchrony is observed in patients with transcatheter closure of ASD, although little negative impacts on the atrial volume and function are demonstrated, which deserves more attention during follow-up of this specific population.