[The clinical spectrum of mastocytosis].

Mastocytosis comprises a heterogeneous spectrum of clinical manifestations, extending from isolated, benign skin infiltrates to systemic involvement, occasionally with a fatal outcome. After a short survey of the morphology and physiology of the mast cell and the skin lesions of mastocytosis, the involvement of internal organs is reviewed and the differential diagnosis is discussed. The options for therapy are discussed, and the need for continuous monitoring of mastocytosis patients is emphasized.