Predictors of remission from chronic depression: a prospective study in a nationally representative sample.

PURPOSE: The aims of this study were to identify predictors of remission from chronic depression in a prospective longitudinal general population survey; second, to determine the relative level functioning and well-being of those in remission.

METHODS

The sample included respondents who met the criteria for major depressive disorder from Wave 1 (2001-2002) and through Wave 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

RESULTS

Panic Disorder, Generalized Anxiety Disorder, Cluster B personality disorders and a history of Physical Abuse were correlated with reduced likelihood of chronic depression remission. The functioning and well-being of the remitted group was below the norm.

CONCLUSIONS

These prognostic factors are similar to those found in clinical samples. Despite remission from chronic depression, a significant proportion have impairments in functioning.